A bluetooth mouse (even when disconnected, but just because it is configured) can wake a PC from sleep mode causing battery drainage.
Issue the following CLI commands for diagnostics and resolution:
powercfg -devicequery wake_armed
(find the device name that will wake the system)
powercfg -devicedisablewake "complete devicename above"
This should return the sleep mode to a nice long battery life.
Here's the background about how I discovered this.